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Karamolegos Winery, founded in 1952 by Artemis Karamolegos, began from a passion for winemaking passed down to him from his beloved grandfather who made wine in a small cave or "canava" using the old traditional methods.

In 2004, a new and modern winery was built to take advantage of the latest in modern technology, while also adhering to the traditional practices passed down from generations. Artemis has been a champion, not only of the main Assyrtiko variety, but has also invested in the cultivation of some of the more obscure indigenous varieties of Santorini, like Mavrotragano, Aidani, Mavrathiro and Voudomato.